Real-Time Phase Masks for Interactive Stimulation of Optogenetic Neurons

Stephan C. Kramer, Johannes Hagemann, D. Russell Luke
Institut fur Numerische und Angewandte Mathematik, Georg-August-Universitat Gottingen
arXiv:1302.0120 [math.OC], 1 Feb 2013


   author={Kramer}, S.~C. and {Hagemann}, J. and {Luke}, D.~R.},

   title={"{Real-Time Phase Masks for Interactive Stimulation of Optogenetic Neurons}"},

   journal={ArXiv e-prints},




   keywords={Mathematics – Optimization and Control, Quantitative Biology – Neurons and Cognition, 68N25, 68N19, 68W10, 68U10, 49M27, 90-04, 90C26, 78M50, 92C20, 85-08},




   adsnote={Provided by the SAO/NASA Astrophysics Data System}


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Experiments with networks of optogenetically altered neurons require stimulation with high spatio-temporal selectivity. Computer-assisted holography is an energy-efficient method for robust and reliable addressing of single neurons on the millisecond-timescale inherent to biologial information processing. We show that real-time control of neurons can be achieved by a CUDA-based hologram computation.
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